# COronary Re-engageMent aFter randOm NavitoR alignmenT (COMFORT STUDY)

> **NCT05779787** · — · RECRUITING · sponsor: **Niguarda Hospital** · enrollment: 100 (estimated)

## Conditions studied

- Aortic Valve Stenosis
- Transcatheter Aortic Valve Replacement

## Interventions

- **PROCEDURE:** TAVR Aligned
- **PROCEDURE:** TAVR Random

## Key facts

- **NCT ID:** NCT05779787
- **Lead sponsor:** Niguarda Hospital
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2023-02-15
- **Primary completion:** 2027-02-15
- **Final completion:** 2027-05-15
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-04-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05779787

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05779787, "COronary Re-engageMent aFter randOm NavitoR alignmenT (COMFORT STUDY)". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT05779787. Licensed CC0.

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