# Study of Efficacy and Safety of Ociperlimab in Combination With Tislelizumab and Platinum-based Doublet Chemotherapy as First-line Treatment for Participants With Locally Advanced or Metastatic NSCLC.

> **NCT05791097** · PHASE3 · WITHDRAWN · sponsor: **Novartis Pharmaceuticals**

## Conditions studied

- Non-small Cell Lung Cancer (NSCLC)

## Interventions

- **DRUG:** Ociperlimab
- **DRUG:** Placebo
- **DRUG:** Tislelizumab
- **DRUG:** Pembrolizumab
- **DRUG:** Carboplatin
- **DRUG:** Cisplatin
- **DRUG:** Pemetrexed
- **DRUG:** Paclitaxel
- **DRUG:** Nab-paclitaxel

## Key facts

- **NCT ID:** NCT05791097
- **Lead sponsor:** Novartis Pharmaceuticals
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2023-07-28
- **Primary completion:** 2027-12-24
- **Final completion:** 2027-12-26
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Business decision, not driven by safety concerns; no new safety signals have been observed in the ociperlimab program.
- **Last updated:** 2023-07-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05791097

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05791097, "Study of Efficacy and Safety of Ociperlimab in Combination With Tislelizumab and Platinum-based Doublet Chemotherapy as First-line Treatment for Participants With Locally Advanced or Metastatic NSCLC.". Retrieved via AI Analytics 2026-06-15 from https://api.ai-analytics.org/clinical/NCT05791097. Licensed CC0.

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