# A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)

> **NCT05795699** · PHASE3 · COMPLETED · sponsor: **Kowa Research Institute, Inc.** · enrollment: 107 (actual)

## Conditions studied

- Fuchs Endothelial Corneal Dystrophy

## Interventions

- **DRUG:** Ripasudil
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05795699
- **Lead sponsor:** Kowa Research Institute, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-03-30
- **Primary completion:** 2025-05-22
- **Final completion:** 2026-02-20
- **Target enrollment:** 107 (ACTUAL)
- **Last updated:** 2026-03-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05795699

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05795699, "A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05795699. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*