# Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)

> **NCT05797649** · — · RECRUITING · sponsor: **Chinese University of Hong Kong** · enrollment: 120 (estimated)

## Conditions studied

- Pleural Effusion
- Heart Failure
- Malignant Neoplasm
- Fluid Overload
- Hypoalbuminemia
- Renal Failure
- Cirrhosis
- Infections

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT05797649
- **Lead sponsor:** Chinese University of Hong Kong
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2023-07-01
- **Primary completion:** 2025-11-30
- **Final completion:** 2025-11-30
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2024-11-13

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05797649

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05797649, "Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT05797649. Licensed CC0.

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