# PD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast Cancer

> **NCT05812326** · PHASE1,PHASE2 · COMPLETED · sponsor: **Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University** · enrollment: 15 (actual)

## Conditions studied

- Advanced Breast Cancer
- Breast Neoplasm Malignant Female

## Interventions

- **DRUG:** AJMUC1- PD-1 gene knockout anti-MUC1 CAR-T cells

## Key facts

- **NCT ID:** NCT05812326
- **Lead sponsor:** Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-05-17
- **Primary completion:** 2022-11-16
- **Final completion:** 2022-11-16
- **Target enrollment:** 15 (ACTUAL)
- **Last updated:** 2023-04-13

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05812326

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05812326, "PD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast Cancer". Retrieved via AI Analytics 2026-07-18 from https://api.ai-analytics.org/clinical/NCT05812326. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*