# Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen

> **NCT05821309** · PHASE4 · RECRUITING · sponsor: **Indiana University** · enrollment: 65 (estimated)

## Conditions studied

- Constipation

## Interventions

- **DRUG:** PEG 3350
- **DRUG:** PEG-3350 with electrolytes
- **DRUG:** Glycerin

## Key facts

- **NCT ID:** NCT05821309
- **Lead sponsor:** Indiana University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-06-08
- **Primary completion:** 2026-07
- **Final completion:** 2026-07
- **Target enrollment:** 65 (ESTIMATED)
- **Last updated:** 2025-07-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05821309

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05821309, "Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT05821309. Licensed CC0.

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