# Incremental Hemodialysis: The TwoPlus Trial

> **NCT05828823** · NA · RECRUITING · sponsor: **Wake Forest University Health Sciences** · enrollment: 350 (estimated)

## Conditions studied

- End-Stage Kidney Disease

## Interventions

- **DEVICE:** Hemodialysis twice weekly
- **OTHER:** Hemodialysis thrice weekly

## Key facts

- **NCT ID:** NCT05828823
- **Lead sponsor:** Wake Forest University Health Sciences
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-02-26
- **Primary completion:** 2027-09
- **Final completion:** 2028-03
- **Target enrollment:** 350 (ESTIMATED)
- **Last updated:** 2026-01-29

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05828823

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05828823, "Incremental Hemodialysis: The TwoPlus Trial". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT05828823. Licensed CC0.

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