Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

NCT05835687 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

48

Enrollment

OTHER

Sponsor class

Conditions

Central Nervous System Neoplasms
Atypical Teratoid/Rhabdoid Tumor
Diffuse Midline Glioma, H3 K27M-Mutant
Ependymoma
High Grade Glioma
Glioblastoma
Medulloblastoma

Interventions

DRUG: B7-H3-CAR T cells

Sponsor

St. Jude Children's Research Hospital