Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma

NCT05836571 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

66

Enrollment

UNKNOWN

Sponsor class

Conditions

Locally Advanced Extraskeletal Myxoid Chondrosarcoma
Locally Advanced Leiomyosarcoma
Locally Advanced Liposarcoma
Locally Advanced Undifferentiated Pleomorphic Sarcoma
Locally Advanced Unresectable Soft Tissue Sarcoma
Metastatic Soft Tissue Sarcoma
Metastatic Undifferentiated Pleomorphic Sarcoma
Unresectable Leiomyosarcoma
Unresectable Liposarcoma
Unresectable Undifferentiated Pleomorphic Sarcoma

Interventions

PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
DRUG: Cabozantinib
PROCEDURE: Computed Tomography
BIOLOGICAL: Ipilimumab
PROCEDURE: Magnetic Resonance Imaging
BIOLOGICAL: Nivolumab

Sponsor

National Cancer Institute LAO