# Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction

> **NCT05839730** · NA · RECRUITING · sponsor: **Medtronic Cardiac Rhythm and Heart Failure** · enrollment: 105 (estimated)

## Conditions studied

- Heart Failure With Preserved Ejection Fraction
- Concentric Hypertrophy

## Interventions

- **DEVICE:** Pacemaker PLR + TRT ON
- **DEVICE:** Pacemaker non-pacing mode or an exertional rate-adaptive pacing mode with no planned pacing at rest.

## Key facts

- **NCT ID:** NCT05839730
- **Lead sponsor:** Medtronic Cardiac Rhythm and Heart Failure
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-09-11
- **Primary completion:** 2026-07
- **Final completion:** 2027-07
- **Target enrollment:** 105 (ESTIMATED)
- **Last updated:** 2026-04-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05839730

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05839730, "Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT05839730. Licensed CC0.

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