# Subclinical Hypothyroidism and Chronic Inflammation in PCOS

> **NCT05842096** · NA · COMPLETED · sponsor: **Jagiellonian University** · enrollment: 158 (actual)

## Conditions studied

- PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
- Subclinical hypothyroïdism
- Hypothalamic-Pituitary-Gonadal Axis Dysfunction

## Interventions

- **DIAGNOSTIC_TEST:** Measurement and comparison of leucocytosis and concentrations of CRP, procalcitonin, fibrinogen, ferritin, IL-1, IL-6, IL-10, TNF-alpha in both study arms
- **DIAGNOSTIC_TEST:** Evaluation of the impact of subclinical hypothyroidism, with present/ absent antithyroid antibodies, on the balance between anti- and pro-inflammatory factors in women in both study arms
- **DIAGNOSTIC_TEST:** Assessment of the impact of imbalance between anti- and pro-inflammatory factors in women with different PCOS and HPOD phenotypes on ovarian reserve indices

## Key facts

- **NCT ID:** NCT05842096
- **Lead sponsor:** Jagiellonian University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-01-01
- **Primary completion:** 2024-12-30
- **Final completion:** 2024-12-30
- **Target enrollment:** 158 (ACTUAL)
- **Last updated:** 2025-04-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05842096

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05842096, "Subclinical Hypothyroidism and Chronic Inflammation in PCOS". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05842096. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*