# A Novel, Potent and Non-addictive Analgesic of Combinations for Knee Replacement Moderate to Severe Pain Management

> **NCT05842733** · PHASE2 · UNKNOWN · sponsor: **Sinew Pharma Inc.** · enrollment: 36 (estimated)

## Conditions studied

- Pain, Postoperative

## Interventions

- **DRUG:** Naldebain
- **DRUG:** SafeTynadol
- **DRUG:** Naldebain + SafeTynadol

## Key facts

- **NCT ID:** NCT05842733
- **Lead sponsor:** Sinew Pharma Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2023-07-25
- **Primary completion:** 2024-12-31
- **Final completion:** 2024-12-31
- **Target enrollment:** 36 (ESTIMATED)
- **Last updated:** 2023-07-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05842733

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05842733, "A Novel, Potent and Non-addictive Analgesic of Combinations for Knee Replacement Moderate to Severe Pain Management". Retrieved via AI Analytics 2026-07-17 from https://api.ai-analytics.org/clinical/NCT05842733. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*