# Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck

> **NCT05845307** · EARLY_PHASE1 · WITHDRAWN · sponsor: **M.D. Anderson Cancer Center**

## Conditions studied

- Squamous Cell Carcinoma of Head and Neck

## Interventions

- **DRUG:** Control Group
- **DRUG:** TTI-101

## Key facts

- **NCT ID:** NCT05845307
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2025-06-20
- **Primary completion:** 2025-11-13
- **Final completion:** 2025-11-13
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** 0 participants
- **Last updated:** 2025-12-08

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05845307

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05845307, "Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT05845307. Licensed CC0.

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