# Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years

> **NCT05846243** · PHASE2,PHASE3 · COMPLETED · sponsor: **Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector"** · enrollment: 334 (actual)

## Conditions studied

- Smallpox
- Monkeypox
- Cowpox
- Vaccinia Virus Infection

## Interventions

- **BIOLOGICAL:** VAC∆6 vaccine (10⁷ PFU)
- **BIOLOGICAL:** VAC∆6 vaccine (10⁶ PFU)
- **BIOLOGICAL:** Live Smallpox Vaccine
- **OTHER:** Placebo (Sodium chloride bufus, 0.9%)

## Key facts

- **NCT ID:** NCT05846243
- **Lead sponsor:** Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector"
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-10-01
- **Primary completion:** 2021-12-31
- **Final completion:** 2022-04-01
- **Target enrollment:** 334 (ACTUAL)
- **Last updated:** 2023-05-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05846243

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05846243, "Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT05846243. Licensed CC0.

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