# Effect of Vitis Vinifera Seed Extract on Venous Reflux Time in Varicose Vein

> **NCT05851183** · PHASE4 · COMPLETED · sponsor: **Yonsei University** · enrollment: 200 (actual)

## Conditions studied

- Varicose Veins of Lower Limb

## Interventions

- **DRUG:** Vitis Vinifera seed extract medication plus therapeutic lifestyle change
- **BEHAVIORAL:** Therapeutic lifestyle change only

## Key facts

- **NCT ID:** NCT05851183
- **Lead sponsor:** Yonsei University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-07-20
- **Primary completion:** 2024-09-30
- **Final completion:** 2025-01-30
- **Target enrollment:** 200 (ACTUAL)
- **Last updated:** 2025-03-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05851183

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05851183, "Effect of Vitis Vinifera Seed Extract on Venous Reflux Time in Varicose Vein". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05851183. Licensed CC0.

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