# Assessment of Combined CCM and ICD Device in HFrEF

> **NCT05855135** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Impulse Dynamics** · enrollment: 300 (estimated)

## Conditions studied

- Heart Failure
- Heart Failure With Reduced Ejection Fraction
- Implantable Defibrillator User
- CCM Therapy
- Non-ischemic Cardiomyopathy
- Ischemic Cardiomyopathy
- Sudden Cardiac Arrest
- Arrhythmias, Cardiac
- Ventricular Tachycardia
- Ventricular Fibrillation

## Interventions

- **DEVICE:** OPTIMIZER® Integra CCM-D System (Treatment Arm)

## Key facts

- **NCT ID:** NCT05855135
- **Lead sponsor:** Impulse Dynamics
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-05-17
- **Primary completion:** 2026-01
- **Final completion:** 2027-07
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2025-07-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05855135

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05855135, "Assessment of Combined CCM and ICD Device in HFrEF". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT05855135. Licensed CC0.

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