# Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial.

> **NCT05872698** · PHASE4 · ACTIVE_NOT_RECRUITING · sponsor: **King's College Hospital NHS Trust** · enrollment: 763 (actual)

## Conditions studied

- Cirrhosis, Liver
- Portal Hypertension
- Variceal Hemorrhage
- Varices, Esophageal

## Interventions

- **DRUG:** Carvedilol
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05872698
- **Lead sponsor:** King's College Hospital NHS Trust
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2019-04-01
- **Primary completion:** 2026-12
- **Final completion:** 2026-12
- **Target enrollment:** 763 (ACTUAL)
- **Last updated:** 2026-05-01

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05872698

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05872698, "Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial.". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT05872698. Licensed CC0.

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