# A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

> **NCT05877196** · NA · RECRUITING · sponsor: **Arizona State University** · enrollment: 216 (estimated)

## Conditions studied

- Mild Cognitive Impairment
- Alzheimer Disease
- Cognitive Impairment
- Cognitive Decline
- Memory Loss
- Memory Impairment

## Interventions

- **BEHAVIORAL:** Moderate Intensity Continuous Training (MICT)
- **BEHAVIORAL:** Chair-based Stretch
- **BEHAVIORAL:** High-Intensity Interval Training (HIIT)
- **BEHAVIORAL:** Combined Aerobic Resistance Exercise (CARE)

## Key facts

- **NCT ID:** NCT05877196
- **Lead sponsor:** Arizona State University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-06-22
- **Primary completion:** 2027-04-01
- **Final completion:** 2028-06-30
- **Target enrollment:** 216 (ESTIMATED)
- **Last updated:** 2026-05-05

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05877196

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05877196, "A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT05877196. Licensed CC0.

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