# Cooling in Mild Encephalopathy

> **NCT05889507** · PHASE3 · RECRUITING · sponsor: **Imperial College London** · enrollment: 426 (estimated)

## Conditions studied

- Neonatal Encephalopathy
- Newborn Asphyxia

## Interventions

- **PROCEDURE:** Whole body hypothermia
- **PROCEDURE:** Targeted normothermia
- **OTHER:** Supportive neonatal intensive care
- **DIAGNOSTIC_TEST:** Follow up assessment at 2 years of age

## Key facts

- **NCT ID:** NCT05889507
- **Lead sponsor:** Imperial College London
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-03-15
- **Primary completion:** 2030-01-01
- **Final completion:** 2030-01-01
- **Target enrollment:** 426 (ESTIMATED)
- **Last updated:** 2026-02-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05889507

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05889507, "Cooling in Mild Encephalopathy". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05889507. Licensed CC0.

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