# Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke

> **NCT05892510** · PHASE2,PHASE3 · RECRUITING · sponsor: **University of Melbourne** · enrollment: 462 (estimated)

## Conditions studied

- Ischemic Stroke, Acute
- Cerebrovascular Disorders
- Brain Disorder
- Central Nervous System Diseases

## Interventions

- **DRUG:** Intra-arterial tenecteplase injection at the completion of thrombectomy
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05892510
- **Lead sponsor:** University of Melbourne
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-06-01
- **Primary completion:** 2027-08-30
- **Final completion:** 2027-11-30
- **Target enrollment:** 462 (ESTIMATED)
- **Last updated:** 2026-05-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05892510

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05892510, "Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke". Retrieved via AI Analytics 2026-09-01 from https://api.ai-analytics.org/clinical/NCT05892510. Licensed CC0.

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