# Effects of Sustained-release Oral Sodium Nitrite on Postoperative Pain and Recovery Following Total Knee Arthroplasty

> **NCT05893160** · PHASE1 · WITHDRAWN · sponsor: **University of Alabama at Birmingham**

## Conditions studied

- Pain

## Interventions

- **DRUG:** JAN101 SR
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT05893160
- **Lead sponsor:** University of Alabama at Birmingham
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2026-06-01
- **Primary completion:** 2027-10-01
- **Final completion:** 2028-08-01
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Study withdran per PI's request
- **Last updated:** 2025-06-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05893160

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05893160, "Effects of Sustained-release Oral Sodium Nitrite on Postoperative Pain and Recovery Following Total Knee Arthroplasty". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT05893160. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*