# Diaphragmatic Function as a Biomarker

> **NCT05903001** · — · RECRUITING · sponsor: **RWTH Aachen University** · enrollment: 800 (estimated)

## Conditions studied

- Dyspnea; Asthmatic
- COPD
- Fibrosis
- Pulmonary Hypertension
- Asthma
- Dyspnea

## Interventions

- **DIAGNOSTIC_TEST:** Diaphragm Ultrasound
- **DIAGNOSTIC_TEST:** Intercostal Muscle Ultrasound
- **DIAGNOSTIC_TEST:** Borg scale
- **DIAGNOSTIC_TEST:** MRC Breathlessness Scale
- **DIAGNOSTIC_TEST:** Respiratory Questionaire
- **DIAGNOSTIC_TEST:** GINA classification of Asthma
- **DIAGNOSTIC_TEST:** Measurement of respiratory mouth pressure
- **DIAGNOSTIC_TEST:** SNIP
- **DIAGNOSTIC_TEST:** 6-minute walking distance
- **DIAGNOSTIC_TEST:** 60 seconds sit-to-stand test
- **DIAGNOSTIC_TEST:** Electromyography
- **DIAGNOSTIC_TEST:** Lung Function
- **DIAGNOSTIC_TEST:** CAT-Questionnaire
- **DIAGNOSTIC_TEST:** European Society of Cardiology (ESC)/ European Respiratory Society (ERS) risk group

## Key facts

- **NCT ID:** NCT05903001
- **Lead sponsor:** RWTH Aachen University
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2023-07-01
- **Primary completion:** 2026-12-30
- **Final completion:** 2026-12-30
- **Target enrollment:** 800 (ESTIMATED)
- **Last updated:** 2026-01-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05903001

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05903001, "Diaphragmatic Function as a Biomarker". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05903001. Licensed CC0.

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