# Accelerated Intermittent Theta-Burst Stimulation Ameliorate Major Depressive Disorder by Regulating CAMKII Pathway

> **NCT05913960** · NA · RECRUITING · sponsor: **First Affiliated Hospital of Zhejiang University** · enrollment: 90 (estimated)

## Conditions studied

- Major Depressive Disorder
- Major Depressive Disorder, Recurrent

## Interventions

- **DEVICE:** sham stimulation
- **DEVICE:** accelerated intermittent theta burst stimulation
- **DEVICE:** high frequency stimulation

## Key facts

- **NCT ID:** NCT05913960
- **Lead sponsor:** First Affiliated Hospital of Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-02-09
- **Primary completion:** 2024-03-15
- **Final completion:** 2027-03-15
- **Target enrollment:** 90 (ESTIMATED)
- **Last updated:** 2023-06-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05913960

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05913960, "Accelerated Intermittent Theta-Burst Stimulation Ameliorate Major Depressive Disorder by Regulating CAMKII Pathway". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT05913960. Licensed CC0.

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