# Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

> **NCT05915013** · PHASE1 · RECRUITING · sponsor: **Yale University** · enrollment: 50 (estimated)

## Conditions studied

- Depressive Disorder, Major
- Post Traumatic Stress Disorder

## Interventions

- **DRUG:** Ketamine
- **DRUG:** Perampanel
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05915013
- **Lead sponsor:** Yale University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-09-07
- **Primary completion:** 2032-12
- **Final completion:** 2032-12
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2026-05-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05915013

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05915013, "Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05915013. Licensed CC0.

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