Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

NCT05919108 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

30

Enrollment

OTHER

Sponsor class

Conditions

Anatomic Stage I Breast Cancer
Anatomic Stage II Breast Cancer
Anatomic Stage III Breast Cancer
Invasive Breast Lobular Carcinoma

Interventions

PROCEDURE: Endocrine Therapy
PROCEDURE: Biopsy of breast
DRUG: Neratinib
PROCEDURE: Biospecimen Collection
PROCEDURE: Mammogram
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Breast Surgery
PROCEDURE: Ultrasound

Sponsor

Vanderbilt-Ingram Cancer Center

Collaborators

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