# Mini-dose MTX Plus Standard-dose Steroid for the Initial Treatment of Acute GVHD

> **NCT05921305** · PHASE3 · RECRUITING · sponsor: **Peking University People's Hospital** · enrollment: 218 (estimated)

## Conditions studied

- Acute Graft Versus Host Disease

## Interventions

- **DRUG:** MTX
- **DRUG:** Corticosteroid

## Key facts

- **NCT ID:** NCT05921305
- **Lead sponsor:** Peking University People's Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-08-03
- **Primary completion:** 2026-06-30
- **Final completion:** 2026-09-30
- **Target enrollment:** 218 (ESTIMATED)
- **Last updated:** 2025-06-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05921305

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05921305, "Mini-dose MTX Plus Standard-dose Steroid for the Initial Treatment of Acute GVHD". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT05921305. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*