# Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

> **NCT05932745** · NA · RECRUITING · sponsor: **Yale University** · enrollment: 66 (estimated)

## Conditions studied

- Nicotine Use Disorder

## Interventions

- **OTHER:** E-liquid coolant (No WS-3) for non-menthol (1)
- **OTHER:** E-liquid coolant (No WS-3) for low (0.1%) menthol (1)
- **OTHER:** E-liquid coolant (No WS-3) for high (2.0%) menthol (1)
- **OTHER:** E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2)
- **OTHER:** E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2)
- **OTHER:** E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2)
- **OTHER:** E-liquid coolant (High [2.0%] WS-3) for non-menthol (3)
- **OTHER:** E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3)
- **OTHER:** E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3)
- **OTHER:** E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4)
- **OTHER:** E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4)
- **OTHER:** E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4)
- **OTHER:** E-liquid coolant (High [2.0%] WS-23) for non-menthol (5)
- **OTHER:** E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5)
- **OTHER:** E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5)
- **OTHER:** E-liquid coolant (4% WS-23) for non-menthol (6)
- **OTHER:** E-liquid coolant (4% WS-23) for low (0.1%) menthol (6)
- **OTHER:** E-liquid coolant (4% WS-23) for high (2.0%) menthol (6)

## Key facts

- **NCT ID:** NCT05932745
- **Lead sponsor:** Yale University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-06-20
- **Primary completion:** 2026-05
- **Final completion:** 2026-05
- **Target enrollment:** 66 (ESTIMATED)
- **Last updated:** 2025-12-26

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05932745

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05932745, "Effects of Novel E-cigarette Constituents on Adults TCORS 3.0". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05932745. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*