# Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive Phase II Trial

> **NCT05935761** · PHASE2 · NOT_YET_RECRUITING · sponsor: **VA Office of Research and Development** · enrollment: 108 (estimated)

## Conditions studied

- Chronic Low Back Pain

## Interventions

- **DRUG:** Pregnenolone
- **DRUG:** DHEA
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05935761
- **Lead sponsor:** VA Office of Research and Development
- **Sponsor class:** FED
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-06-01
- **Primary completion:** 2029-10-01
- **Final completion:** 2029-12-31
- **Target enrollment:** 108 (ESTIMATED)
- **Last updated:** 2026-04-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05935761

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05935761, "Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive Phase II Trial". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05935761. Licensed CC0.

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