# A Real-world, Head-to-head Comparison of Dupilumab Versus Mepolizumab in Danish Patients With Chronic Rhinosinusitis With Nasal Polyps

> **NCT05942222** · PHASE4 · ACTIVE_NOT_RECRUITING · sponsor: **Rigshospitalet, Denmark** · enrollment: 220 (estimated)

## Conditions studied

- Chronic Rhinosinusitis With Nasal Polyps
- Asthma; Eosinophilic
- Eosinophilia

## Interventions

- **BIOLOGICAL:** dupilumab
- **BIOLOGICAL:** mepolizumab

## Key facts

- **NCT ID:** NCT05942222
- **Lead sponsor:** Rigshospitalet, Denmark
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-04-27
- **Primary completion:** 2026-04-01
- **Final completion:** 2026-05-01
- **Target enrollment:** 220 (ESTIMATED)
- **Last updated:** 2025-07-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05942222

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05942222, "A Real-world, Head-to-head Comparison of Dupilumab Versus Mepolizumab in Danish Patients With Chronic Rhinosinusitis With Nasal Polyps". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05942222. Licensed CC0.

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