# Base Edited CAR T Cells Against AML: Deep Conditioning Ahead of Allogeneic Stem Cell Transplantation

> **NCT05942599** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Great Ormond Street Hospital for Children NHS Foundation Trust** · enrollment: 10 (estimated)

## Conditions studied

- Relapsed Acute Myeloid Leukaemia

## Interventions

- **BIOLOGICAL:** Cryopreserved BE CAR33 T Cells (BE752TBTTBCAR33PBL)

## Key facts

- **NCT ID:** NCT05942599
- **Lead sponsor:** Great Ormond Street Hospital for Children NHS Foundation Trust
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-07-21
- **Primary completion:** 2026-06-01
- **Final completion:** 2026-06-01
- **Target enrollment:** 10 (ESTIMATED)
- **Last updated:** 2026-01-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05942599

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05942599, "Base Edited CAR T Cells Against AML: Deep Conditioning Ahead of Allogeneic Stem Cell Transplantation". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05942599. Licensed CC0.

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