# CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML

> **NCT05945849** · PHASE1 · RECRUITING · sponsor: **University of Pennsylvania** · enrollment: 16 (estimated)

## Conditions studied

- Leukemia, Myeloid, Acute

## Interventions

- **BIOLOGICAL:** CD33KO-HSPC; CART33

## Key facts

- **NCT ID:** NCT05945849
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-02-23
- **Primary completion:** 2029-02-23
- **Final completion:** 2044-02-23
- **Target enrollment:** 16 (ESTIMATED)
- **Last updated:** 2025-06-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05945849

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05945849, "CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT05945849. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*