# Effect of Orexin System on Nicotine Addiction and Its Neural Mechanism

> **NCT05947162** · NA · NOT_YET_RECRUITING · sponsor: **Shenzhen Kangning Hospital** · enrollment: 150 (estimated)

## Conditions studied

- Tobacco Use Disorder

## Interventions

- **BEHAVIORAL:** extinction training (nicotine cues)
- **BEHAVIORAL:** extinction training (neutral cues)
- **BEHAVIORAL:** Time-restricted smoking cessation
- **BEHAVIORAL:** Time-restricted fasting
- **BEHAVIORAL:** Time-restricted fasting with food supplemnet

## Key facts

- **NCT ID:** NCT05947162
- **Lead sponsor:** Shenzhen Kangning Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2023-11-01
- **Primary completion:** 2027-07-31
- **Final completion:** 2027-07-31
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2023-10-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05947162

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05947162, "Effect of Orexin System on Nicotine Addiction and Its Neural Mechanism". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT05947162. Licensed CC0.

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