# A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants

> **NCT05966688** · PHASE1 · COMPLETED · sponsor: **Spero Therapeutics** · enrollment: 39 (actual)

## Conditions studied

- Healthy Volunteers

## Interventions

- **DRUG:** SPR720
- **DRUG:** Azithromycin
- **DRUG:** Ethambutol

## Key facts

- **NCT ID:** NCT05966688
- **Lead sponsor:** Spero Therapeutics
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-08-04
- **Primary completion:** 2024-01-30
- **Final completion:** 2024-02-04
- **Target enrollment:** 39 (ACTUAL)
- **Last updated:** 2024-03-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05966688

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05966688, "A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT05966688. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*