# The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.

> **NCT05973786** · PHASE3 · RECRUITING · sponsor: **Dr. Inge Winter** · enrollment: 418 (estimated)

## Conditions studied

- Bipolar Depression

## Interventions

- **DRUG:** Escitalopram
- **DRUG:** Sertraline
- **DRUG:** Venlafaxine
- **DRUG:** Lithium
- **DRUG:** Valproate acid
- **DRUG:** Quetiapine
- **DRUG:** Bupropion

## Key facts

- **NCT ID:** NCT05973786
- **Lead sponsor:** Dr. Inge Winter
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-02-11
- **Primary completion:** 2028-06-30
- **Final completion:** 2028-06-30
- **Target enrollment:** 418 (ESTIMATED)
- **Last updated:** 2025-09-26

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05973786

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05973786, "The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05973786. Licensed CC0.

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