# Comparative Study of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty

> **NCT05980442** · — · RECRUITING · sponsor: **Aesculap AG** · enrollment: 140 (estimated)

## Conditions studied

- Osteoarthritis, Knee
- Joint Diseases
- Rheumatoid Arthritis of Knee
- Posttraumatic Arthropathy

## Interventions

- **DEVICE:** Navigated total knee arthroplasty
- **DEVICE:** Robot assisted total knee arthroplasty

## Key facts

- **NCT ID:** NCT05980442
- **Lead sponsor:** Aesculap AG
- **Sponsor class:** INDUSTRY
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-07-03
- **Primary completion:** 2027-12
- **Final completion:** 2028-12
- **Target enrollment:** 140 (ESTIMATED)
- **Last updated:** 2026-03-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05980442

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05980442, "Comparative Study of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05980442. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*