# Effect of Menopause Hormone Therapy In Postmenopausal Women With CSVD And MCI

> **NCT05982470** · PHASE2 · UNKNOWN · sponsor: **Beijing Tiantan Hospital** · enrollment: 328 (estimated)

## Conditions studied

- Cerebral Small Vessel Diseases
- Postmenopausal Symptoms
- Mild Cognitive Impairment
- White Matter Hyperintensity

## Interventions

- **DRUG:** Estradiol Gel
- **DRUG:** Estradiol Placebo Gel
- **DRUG:** Progesterone Soft Capsule
- **DRUG:** Progesterone Placebo Soft Capsule

## Key facts

- **NCT ID:** NCT05982470
- **Lead sponsor:** Beijing Tiantan Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2023-08-18
- **Primary completion:** 2025-06-01
- **Final completion:** 2025-10-01
- **Target enrollment:** 328 (ESTIMATED)
- **Last updated:** 2023-08-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05982470

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05982470, "Effect of Menopause Hormone Therapy In Postmenopausal Women With CSVD And MCI". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05982470. Licensed CC0.

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