# Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer

> **NCT05992272** · — · RECRUITING · sponsor: **Charite University, Berlin, Germany** · enrollment: 300 (estimated)

## Conditions studied

- Alcohol Use Disorder (AUD)
- Alcoholism
- Substance Use Disorders
- Smoking, Tobacco
- Stress Reaction
- Stress

## Interventions

- **BIOLOGICAL:** fMRI imaging (BOLD)
- **BIOLOGICAL:** sMRI (structure)
- **BEHAVIORAL:** Trier Social Stress Test
- **BEHAVIORAL:** PIT paradigm
- **BEHAVIORAL:** Counting Stroop task
- **BEHAVIORAL:** No-go Simon task
- **DIAGNOSTIC_TEST:** Stop Signal Task
- **DIAGNOSTIC_TEST:** blood samples
- **DIAGNOSTIC_TEST:** questionnaires for chronic stress
- **DIAGNOSTIC_TEST:** hair samples
- **DIAGNOSTIC_TEST:** saliva samples
- **DIAGNOSTIC_TEST:** EMA assessment
- **DIAGNOSTIC_TEST:** clinical diagnostic

## Key facts

- **NCT ID:** NCT05992272
- **Lead sponsor:** Charite University, Berlin, Germany
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2020-11-24
- **Primary completion:** 2024-12-31
- **Final completion:** 2024-12-31
- **Target enrollment:** 300 (ESTIMATED)
- **Last updated:** 2024-08-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05992272

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05992272, "Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT05992272. Licensed CC0.

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