# Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy

> **NCT05999851** · NA · RECRUITING · sponsor: **IRCCS Azienda Ospedaliero-Universitaria di Bologna** · enrollment: 400 (estimated)

## Conditions studied

- Preeclampsia
- Hypertensive Disorder of Pregnancy

## Interventions

- **DEVICE:** Arterial applanation tonometry
- **DEVICE:** In vivo endothelial glycocalyx measurement
- **DIAGNOSTIC_TEST:** Serum markers of angiogenesis and endothelial dysfunction
- **DIAGNOSTIC_TEST:** Blood chemistry test
- **DIAGNOSTIC_TEST:** Serum xanthine oxidase activity

## Key facts

- **NCT ID:** NCT05999851
- **Lead sponsor:** IRCCS Azienda Ospedaliero-Universitaria di Bologna
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-09-01
- **Primary completion:** 2026-05
- **Final completion:** 2031-09
- **Target enrollment:** 400 (ESTIMATED)
- **Last updated:** 2026-01-22

## Collaborators

- University of Bologna

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05999851

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05999851, "Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy". Retrieved via AI Analytics 2026-08-02 from https://api.ai-analytics.org/clinical/NCT05999851. Licensed CC0.

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