# Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) to Tyrosine Kinase Inhibitor in Oligoprogressive Oncogenic Positive Non-Small Cell Lung Carcinoma

> **NCT06014827** · PHASE2 · RECRUITING · sponsor: **City of Hope Medical Center** · enrollment: 32 (estimated)

## Conditions studied

- Lung Non-Small Cell Carcinoma
- Stage IV Lung Cancer AJCC v8

## Interventions

- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Computed Tomography
- **DRUG:** Osimertinib
- **PROCEDURE:** Positron Emission Tomography
- **RADIATION:** Stereotactic Body Radiation Therapy
- **OTHER:** Survey Administration

## Key facts

- **NCT ID:** NCT06014827
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-10-09
- **Primary completion:** 2026-07-11
- **Final completion:** 2026-07-11
- **Target enrollment:** 32 (ESTIMATED)
- **Last updated:** 2026-05-07

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06014827

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06014827, "Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) to Tyrosine Kinase Inhibitor in Oligoprogressive Oncogenic Positive Non-Small Cell Lung Carcinoma". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT06014827. Licensed CC0.

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