# Fraction Dose Escalation of Split-course Hypofractionated Concurrent Chemoradiotherapy Following Induction Chemo-immunotherapy in Unresectable Locally Advanced Esophageal Squamous Carcinoma: a Phase I Study.

> **NCT06020885** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Sun Yat-sen University** · enrollment: 18 (estimated)

## Conditions studied

- Esophageal Squamous Cell Carcinoma

## Interventions

- **RADIATION:** Split-course hypo-CCRT
- **DRUG:** Induction chemo-immunotherapy
- **DRUG:** Concurrent chemotherapy

## Key facts

- **NCT ID:** NCT06020885
- **Lead sponsor:** Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2023-08-31
- **Primary completion:** 2025-10-30
- **Final completion:** 2025-10-30
- **Target enrollment:** 18 (ESTIMATED)
- **Last updated:** 2025-07-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06020885

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06020885, "Fraction Dose Escalation of Split-course Hypofractionated Concurrent Chemoradiotherapy Following Induction Chemo-immunotherapy in Unresectable Locally Advanced Esophageal Squamous Carcinoma: a Phase I Study.". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT06020885. Licensed CC0.

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