# Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

> **NCT06022939** · PHASE3 · RECRUITING · sponsor: **SWOG Cancer Research Network** · enrollment: 338 (estimated)

## Conditions studied

- AL Amyloidosis

## Interventions

- **PROCEDURE:** Autologous Hematopoietic Stem Cell Transplantation
- **PROCEDURE:** Biopsy
- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Bone Marrow Aspiration
- **PROCEDURE:** Bone Marrow Biopsy
- **DRUG:** Bortezomib
- **PROCEDURE:** Computed Tomography
- **DRUG:** Cyclophosphamide
- **DRUG:** Daratumumab and Hyaluronidase-fihj
- **DRUG:** Dexamethasone
- **PROCEDURE:** Echocardiography
- **PROCEDURE:** Magnetic Resonance Imaging
- **DRUG:** Melphalan
- **PROCEDURE:** Positron Emission Tomography
- **PROCEDURE:** Stem Cell Isolation
- **OTHER:** Survey Administration

## Key facts

- **NCT ID:** NCT06022939
- **Lead sponsor:** SWOG Cancer Research Network
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-07-01
- **Primary completion:** 2030-07-29
- **Final completion:** 2030-10-29
- **Target enrollment:** 338 (ESTIMATED)
- **Last updated:** 2026-05-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06022939

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06022939, "Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis". Retrieved via AI Analytics 2026-08-21 from https://api.ai-analytics.org/clinical/NCT06022939. Licensed CC0.

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