# Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan

> **NCT06034821** · PHASE4 · ENROLLING_BY_INVITATION · sponsor: **Brigham and Women's Hospital** · enrollment: 1500 (estimated)

## Conditions studied

- Acute Suicidal Depression (ASD)

## Interventions

- **DRUG:** Subanesthetic dose intravenous ketamine (KET)
- **DEVICE:** Electroconvulsive therapy (ECT)

## Key facts

- **NCT ID:** NCT06034821
- **Lead sponsor:** Brigham and Women's Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2023-10-01
- **Primary completion:** 2030-10-01
- **Final completion:** 2030-12-01
- **Target enrollment:** 1500 (ESTIMATED)
- **Last updated:** 2025-12-15

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06034821

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06034821, "Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan". Retrieved via AI Analytics 2026-07-10 from https://api.ai-analytics.org/clinical/NCT06034821. Licensed CC0.

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