# Combination of Buffered Anesthetic to Treat Mandibular Molars

> **NCT06047366** · PHASE4 · TERMINATED · sponsor: **Indiana University** · enrollment: 40 (actual)

## Conditions studied

- Symptomatic Irreversible Pulpitis

## Interventions

- **DRUG:** Sodium bicarbonate
- **DRUG:** Lidocaine w/ epi
- **DRUG:** Articaine w/ epi
- **DRUG:** Mepivacaine plain

## Key facts

- **NCT ID:** NCT06047366
- **Lead sponsor:** Indiana University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2023-12-05
- **Primary completion:** 2024-05-15
- **Final completion:** 2024-05-15
- **Target enrollment:** 40 (ACTUAL)
- **Why stopped:** Student PI is preparing for graduation and cannot complete the study as planned.
- **Last updated:** 2025-05-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06047366

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06047366, "Combination of Buffered Anesthetic to Treat Mandibular Molars". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT06047366. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*