# Somatic Mosaicism in Twins Discordant for Childhood Cancer

> **NCT06054295** · — · RECRUITING · sponsor: **Children's Oncology Group** · enrollment: 50 (estimated)

## Conditions studied

- Pediatric Central Nervous System Tumor
- Central Nervous System Tumor
- Discordant Twin
- Somatic Mutation

## Interventions

- **OTHER:** Biospecimen collection
- **OTHER:** Questionnaire Administration

## Key facts

- **NCT ID:** NCT06054295
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-06-03
- **Primary completion:** 2026-06-30
- **Final completion:** 2027-06-30
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2025-12-16

## Collaborators

- National Cancer Institute (NCI)

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06054295

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06054295, "Somatic Mosaicism in Twins Discordant for Childhood Cancer". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT06054295. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*