# A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria

> **NCT06069544** · PHASE1,PHASE2 · COMPLETED · sponsor: **BioNTech SE** · enrollment: 163 (actual)

## Conditions studied

- Malaria

## Interventions

- **BIOLOGICAL:** BNT165e
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT06069544
- **Lead sponsor:** BioNTech SE
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-11-13
- **Primary completion:** 2025-05-28
- **Final completion:** 2026-03-20
- **Target enrollment:** 163 (ACTUAL)
- **Last updated:** 2026-04-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06069544

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06069544, "A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT06069544. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*