# Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance

> **NCT06070961** · — · RECRUITING · sponsor: **Fondazione Italiana Linfomi - ETS** · enrollment: 56 (estimated)

## Conditions studied

- Follicular Lymphoma

## Interventions

- **DIAGNOSTIC_TEST:** Cellular immunity vs SARS-CoV-2
- **DIAGNOSTIC_TEST:** Humoral immunity vs SARS-CoV-2
- **DIAGNOSTIC_TEST:** Cellular immunity vs Varicella Zoster Virus
- **DIAGNOSTIC_TEST:** Humoral immunity vs Varicella Zoster Virus
- **DIAGNOSTIC_TEST:** Diphtheria toxin-binding IgG
- **DIAGNOSTIC_TEST:** Tetanus toxoid-binding IgG
- **DIAGNOSTIC_TEST:** T-cell populations and markers characterization

## Key facts

- **NCT ID:** NCT06070961
- **Lead sponsor:** Fondazione Italiana Linfomi - ETS
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2024-05-07
- **Primary completion:** 2027-05
- **Final completion:** 2027-05
- **Target enrollment:** 56 (ESTIMATED)
- **Last updated:** 2025-06-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06070961

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06070961, "Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance". Retrieved via AI Analytics 2026-09-04 from https://api.ai-analytics.org/clinical/NCT06070961. Licensed CC0.

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