# A Randomized Neuroimaging Trial of Psilocybin in Depression

> **NCT06072898** · PHASE2 · RECRUITING · sponsor: **Sunnybrook Health Sciences Centre** · enrollment: 50 (estimated)

## Conditions studied

- Depressive Disorder
- Major Depressive Disorder

## Interventions

- **DRUG:** Psilocybin
- **OTHER:** Microcrystalline cellulose
- **BEHAVIORAL:** Supportive psychotherapy

## Key facts

- **NCT ID:** NCT06072898
- **Lead sponsor:** Sunnybrook Health Sciences Centre
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-05-28
- **Primary completion:** 2028-05
- **Final completion:** 2029-05
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2026-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06072898

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06072898, "A Randomized Neuroimaging Trial of Psilocybin in Depression". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06072898. Licensed CC0.

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