# LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

> **NCT06073431** · — · RECRUITING · sponsor: **University of Rochester** · enrollment: 800 (estimated)

## Conditions studied

- Advanced Colorectal Carcinoma
- Advanced Lung Non-Small Cell Carcinoma
- Advanced Pancreatic Adenocarcinoma
- Stage IV Colorectal Cancer AJCC v8
- Stage IV Lung Cancer AJCC v8
- Stage IV Pancreatic Cancer AJCC v8
- Unresectable Colorectal Carcinoma
- Unresectable Lung Non-Small Cell Carcinoma
- Unresectable Pancreatic Adenocarcinoma

## Interventions

- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Computed Tomography
- **OTHER:** Electronic Health Record Review
- **OTHER:** Medical Device Usage and Evaluation
- **OTHER:** Physical Performance Testing
- **PROCEDURE:** Positron Emission Tomography
- **OTHER:** Survey Administration

## Key facts

- **NCT ID:** NCT06073431
- **Lead sponsor:** University of Rochester
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2023-12-04
- **Primary completion:** 2027-11-13
- **Final completion:** 2028-09-30
- **Target enrollment:** 800 (ESTIMATED)
- **Last updated:** 2026-01-09

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06073431

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06073431, "LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT06073431. Licensed CC0.

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