# Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled Trial

> **NCT06081335** · NA · COMPLETED · sponsor: **Ain Shams University** · enrollment: 20 (actual)

## Conditions studied

- Pain, Postoperative
- Irreversible Pulpitis
- Apical Periodontitis

## Interventions

- **DEVICE:** EdgeEndo x7 continuous rotation files
- **DEVICE:** EdgeOne Fire reciprocating files

## Key facts

- **NCT ID:** NCT06081335
- **Lead sponsor:** Ain Shams University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-03-15
- **Primary completion:** 2023-04-05
- **Final completion:** 2023-06-05
- **Target enrollment:** 20 (ACTUAL)
- **Last updated:** 2023-11-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06081335

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06081335, "Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled Trial". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT06081335. Licensed CC0.

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