# Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy

> **NCT06092957** · PHASE3 · RECRUITING · sponsor: **Sun Yat-sen University** · enrollment: 504 (estimated)

## Conditions studied

- Nasopharyngeal Carcinoma
- De-escalation Therapy

## Interventions

- **DRUG:** Cisplatin-based induction chemotherapy
- **DRUG:** Full course of PD-1/PD-L1 blockades
- **RADIATION:** Reduced-dose IMRT
- **RADIATION:** Standard-dose IMRT
- **DRUG:** Concurrent Chemotherapy

## Key facts

- **NCT ID:** NCT06092957
- **Lead sponsor:** Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-10-09
- **Primary completion:** 2029-10-30
- **Final completion:** 2031-10-30
- **Target enrollment:** 504 (ESTIMATED)
- **Last updated:** 2023-12-15

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT06092957

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT06092957, "Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT06092957. Licensed CC0.

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